Document Detail

Follow-up of hydration and sedation in the pretherapy of premature labor.
MedLine Citation:
PMID:  6137954     Owner:  NLM     Status:  MEDLINE    
Intravenous fluids and sedation with 8 mg of morphine sulfate intramuscularly has been used for the last 12 years at our institution to define the patients in "real" premature labor. Only those who continue to have uterine contractions after this pretreatment are considered in actual premature labor. One hundred eighty-four pregnant patients with singleton pregnancies were evaluated after they were treated with hydration and sedation for the presence of regular uterine contractions. Fifty-five percent of the patients responded to hydration and sedation, and the rest required the use of tocolytic therapy. In the tocolytic therapy group, 11% gave birth to infants who were small for gestational age. The patients who responded to hydration and sedation had a 2.6-fold increase of delivering prematurely when compared to the general population. However, more than 85% of the patients who received only hydration and sedation were delivered more than 2 weeks after the first episode and most of them were delivered at term. Therefore, the use of hydration and sedation seems a useful and safe clinical test to determine patients in real premature labor. Patients who respond to hydration and therapy constitute a "high-risk group" and should be managed accordingly.
G Valenzuela; S Cline; R H Hayashi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  147     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  396-8     Citation Subset:  AIM; IM    
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MeSH Terms
Adrenergic beta-Agonists / therapeutic use
Combined Modality Therapy
Fluid Therapy*
Hypnotics and Sedatives / therapeutic use*
Morphine / therapeutic use
Obstetric Labor, Premature / prevention & control*
Prospective Studies
Reg. No./Substance:
0/Adrenergic beta-Agonists; 0/Hypnotics and Sedatives; 57-27-2/Morphine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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