Document Detail

Folliculitis-perifolliculitis related to erlotinib therapy spares previously irradiated skin.
MedLine Citation:
PMID:  19103369     Owner:  NLM     Status:  MEDLINE    
Erlotinib, a specific epidermal growth factor receptor tyrosine kinase inhibitor, is used to treat various metastatic cancers. It is known to cause an acneiform rash. Herein, we report a case where the rash spared the previous radiotherapy field. A limitation of this study is that it is an anecdotal case report. Further research into the pathologic process of the rash is warranted to understand the reason for its absence in the irradiated skin.
Jayati Acharya; Calum Lyon; David M Bottomley
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  60     ISSN:  1097-6787     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-23     Completed Date:  2009-01-22     Revised Date:  2013-06-03    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  154-7     Citation Subset:  IM    
Department of Clinical Oncology, St James's Institute of Oncology, Leeds, United Kingdom.
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MeSH Terms
Carcinoma, Non-Small-Cell Lung / drug therapy,  radiotherapy
Folliculitis / chemically induced*
Lung Neoplasms / drug therapy,  radiotherapy
Protein Kinase Inhibitors / adverse effects*
Quinazolines / adverse effects*
Skin / radiation effects*
Reg. No./Substance:
0/Protein Kinase Inhibitors; 0/Quinazolines; J4T82NDH7E/erlotinib

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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