Document Detail


Follicular non-Hodgkin's lymphoma.
MedLine Citation:
PMID:  20380942     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Follicular non-Hodgkin's lymphoma (NHL) is a unique subtype of NHL, which is indolent, incurable with a high prevalence of residual mass after treatment, and may transform to more aggressive NHL. The aim of this review is to (1) describe the histological and flow cytometry characteristics of follicular NHL; (2) introduce the Follicular Lymphoma International Prognostic Index 2 (FLIPI-2), which allows better treatment selection and patient stratification for clinical trials; (3) illustrate the classic and atypical ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and positron-emission tomography (PET)/CT appearance of follicular NHL; and (4) characterize the appearance of nodal and extranodal follicular NHL with pathological correlation. Imaging is essential in every step of the management of patients with follicular lymphoma. Overall survival is improved with better predictive tools and new targeted biological therapies. Radiologists should be aware of possible active residual mass, indolent recurrence, transformation, and association with other primary cancers in patients treated for follicular lymphoma.
Authors:
D Hayashi; J C Lee; B Devenney-Cakir; S Zaim; S Ounadjela; P Solal-Céligny; M Juweid; A Guermazi
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2010-03-15
Journal Detail:
Title:  Clinical radiology     Volume:  65     ISSN:  1365-229X     ISO Abbreviation:  Clin Radiol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-12     Completed Date:  2010-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1306016     Medline TA:  Clin Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  408-20     Citation Subset:  IM    
Affiliation:
Department of Radiology, Boston University School of Medicine, FGH Building, 3rd Floor, Boston, MA 02118, USA. Daichi.Hayashi@bmc.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cell Transformation, Neoplastic / pathology
Diagnostic Imaging / methods*
Female
Humans
Lymphoma, Follicular / diagnosis*,  pathology,  therapy
Male
Middle Aged
Neoplasm Recurrence, Local / diagnosis,  pathology
Neoplasm Staging / methods
Neoplasm, Residual
Neoplasms, Second Primary / diagnosis,  pathology
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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