Document Detail


Follicular mucinosis associated with scarring alopecia, oligoclonal T-cell receptor V beta expansion, and Staphylococcus aureus: when does follicular mucinosis become mycosis fungoides?
MedLine Citation:
PMID:  9366845     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A diagnosis of alopecia mucinosa, occurring as a single scalp lesion, was made in a 40-year-old white woman who had a history of trauma. Follicular mucinosis, Staphylococcus aureus, and oligoclonal expansion of the T-cell receptor V beta chain genes 6 and 7 were present in the skin. Epidermotropic T-cell skin diseases with oligoclonal T-cell proliferations may be the result of HLA- and cytokine-determined reaction patterns to persistent antigens.
Authors:
C M Jackow; E Papadopoulos; B Nelson; J A Tschen; G Heatherington; M Duvic
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  37     ISSN:  0190-9622     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  1997 Nov 
Date Detail:
Created Date:  1997-11-26     Completed Date:  1997-11-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  828-31     Citation Subset:  IM    
Affiliation:
Department of Dermatology, University of Texas Medical School, Houston 77030, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Alopecia / etiology*,  pathology
Biopsy
Cicatrix / etiology*
Diagnosis, Differential
Female
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Humans
Mucinosis, Follicular / diagnosis*,  microbiology
Mycosis Fungoides / immunology,  pathology*
Polymerase Chain Reaction
Precancerous Conditions / immunology,  pathology*
Receptors, Antigen, T-Cell / genetics
Scalp / injuries,  microbiology,  pathology,  surgery
Skin Neoplasms / immunology,  pathology*
Staphylococcus aureus / isolation & purification
T-Lymphocytes / pathology
Grant Support
ID/Acronym/Agency:
AR-39915/AR/NIAMS NIH HHS
Chemical
Reg. No./Substance:
0/Receptors, Antigen, T-Cell

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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