| Follicular-fluid anti-Mullerian hormone concentrations are predictive of assisted reproduction outcome in PCOS patients. | |
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MedLine Citation:
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PMID: 20021712 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Serum anti-Mullerian hormone (AMH) concentrations constitute a sensitive marker for ovarian ageing. In addition, concentrations of AMH in the follicular fluid constitute a useful marker of embryo implantation in assisted reproduction cycles. The present study measured serum and follicular-fluid AMH concentrations on the day of oocyte retrieval. These data showed that clinical pregnancy rates (25.0, 34.1 and 42.1%, respectively, P < 0.001), embryo implantation rates (24.3, 35.0 and 44.4%, respectively, P < 0.001) and fertilization rates (59.2, 70.9 and 79.5%, respectively, P < 0.001) were markedly different among the low, moderate and high follicular-fluid AMH groups but not among the different serum AMH concentration groups. Follicular-fluid AMH concentrations were negatively correlated with follicular-fluid oestradiol concentrations. The results of this study suggest that follicular-fluid AMH concentration on the day of oocyte retrieval would appear to better reflect the reproductive outcome in PCOS patients undergoing assisted reproduction. |
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Authors:
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Recai Pabuccu; Cemil Kaya; Gamze Sinem Cağlar; Efser Oztas; Hakan Satiroglu |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Reproductive biomedicine online Volume: 19 ISSN: 1472-6491 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-12-21 Completed Date: 2010-09-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: England |
Other Details:
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Languages: eng Pagination: 631-7 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Faculty of Medicine, Ufuk University, Ankara, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Mullerian Hormone / blood, metabolism* Biological Markers / blood, metabolism Embryo Implantation Female Fertilization Follicular Fluid / metabolism* Humans Infertility, Female / etiology Oocyte Retrieval Ovulation Induction Polycystic Ovary Syndrome / complications* Pregnancy Pregnancy Outcome* Reproductive Techniques, Assisted* |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 80497-65-0/Anti-Mullerian Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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