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Follicular dendritic cell sarcoma of the liver: unusual presentation of a rare tumor and literature review.
MedLine Citation:
PMID:  21813397     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Hepatic follicular dendritic cell (FDC) sarcoma is an extremely rare neoplasm. Most commonly, FDC sarcoma presents as a solitary mass in lymph nodes, however, several extra-nodal locations have been identified.
METHODS: We report a case of a 53-year-old female who presented with symptoms of abdominal pain, fever, anemia, and jaundice. After an extensive review of the literature, we have found only 12 cases of hepatic FDC sarcoma.
RESULTS: The tumor was 11.5 cm in diameter and composed of spindle and epithelioid cells with ovoid nuclei and associated with mixed inflammatory infiltrate. Immunohistochemical stains were positive for CD35 and CD21. The patient underwent a left hepatic lobectomy.
CONCLUSIONS: Liver follicular dendritic cell sarcoma is a very rare tumor. Most cases present with abdominal pain and weight loss, and most of them can be managed by hepatic resection with excellent short-term outcomes.
Paulo N Martins; Sanjay Reddy; Ann-Britt Martins; Marcelo Facciuto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hepatobiliary & pancreatic diseases international : HBPD INT     Volume:  10     ISSN:  1499-3872     ISO Abbreviation:  HBPD INT     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101151457     Medline TA:  Hepatobiliary Pancreat Dis Int     Country:  China    
Other Details:
Languages:  eng     Pagination:  443-5     Citation Subset:  IM    
Department of Surgery, Division of Hepatobiliary Surgery and Transplantation, New York Medical College, New York, USA.
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