| Folic Acid supplementation and pregnancy: more than just neural tube defect prevention. | |
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MedLine Citation:
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PMID: 22102928 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Folate (vitamin B(9)) is an essential nutrient that is required for DNA replication and as a substrate for a range of enzymatic reactions involved in amino acid synthesis and vitamin metabolism. Demands for folate increase during pregnancy because it is also required for growth and development of the fetus. Folate deficiency has been associated with abnormalities in both mothers (anemia, peripheral neuropathy) and fetuses (congenital abnormalities). This article reviews the metabolism of folic acid, the appropriate use of folic acid supplementation in pregnancy, and the potential benefits of folic acid, as well as the possible supplementation of l-methylfolate for the prevention of pregnancy-related complications other than neural tube defects. |
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Authors:
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James A Greenberg; Stacey J Bell; Yong Guan; Yan-Hong Yu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Reviews in obstetrics and gynecology Volume: 4 ISSN: 1941-2797 ISO Abbreviation: Rev Obstet Gynecol Publication Date: 2011 |
Date Detail:
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Created Date: 2011-11-21 Completed Date: 2011-11-23 Revised Date: 2011-11-23 |
Medline Journal Info:
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Nlm Unique ID: 101479674 Medline TA: Rev Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 52-9 Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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