| Folic Acid and birth defects: a case study (iran). | |
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MedLine Citation:
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PMID: 22229095 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The aim of this study was to evaluate the impact of folic acid use in pregnancy for the reduction of neural tube defects (NTDs) in the northwest region of Iran. We studied 243 women with pregnancies complicated by some forms of birth defect(s). These patients were identified by medical diagnostic tests as having a fetus with some types of congenital anomalies. The prevalence of NTDs among pregnant women who were referred for therapeutic termination of pregnancy was 24.7 percent. Consumption of folic acid prevented NTDs by 79 percent (Odds Ratio = 0.21, CI 95%: 0.12-0.40) and 94 percent (Odds Ratio = 0.06, CI 95%: 0.03-0.15) compared to pregnancies complicated by other anomalies and normal pregnancies, respectively. Hydrops fetalis, hydrocephaly, Down syndrome, and limb anomalies did not have any significant association with the folic acid use. Along with the advice for the consumption of folic acid for pregnant women, they should be offered prenatal screening or diagnostic tests to identify fetal abnormalities for possible termination of pregnancy. |
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Authors:
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Mohammad Bager Hosseini; Zhila Khamnian; Saeed Dastgiri; Bahram Samadi Raad; Yalda Ravanshad |
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Publication Detail:
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Type: Journal Article Date: 2011-12-20 |
Journal Detail:
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Title: Journal of pregnancy Volume: 2011 ISSN: 2090-2735 ISO Abbreviation: J Pregnancy Publication Date: 2011 |
Date Detail:
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Created Date: 2012-01-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101553823 Medline TA: J Pregnancy Country: Egypt |
Other Details:
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Languages: eng Pagination: 370458 Citation Subset: - |
Affiliation:
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Department of Neonatology, Children Health Research Centre, Tabriz University of Medical Sciences, Tabriz 515665931, Iran. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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