Document Detail


Folate and vitamin B12 levels in patients with oral lichen planus, stomatitis or glossitis.
MedLine Citation:
PMID:  11944731     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Forty-one patients with oral lesions and symptoms were enrolled in the study. Their ages ranged from 16 to 79 years with a mean age of 48.5 years. They were divided into two groups. Group I consisted of 25 patients with oral lichen planus and group II consisted of 16 patients with stomatitis or glossitis. Their complete blood counts, hemoglobin typing, serum and red cell folate, and serum vitamin B12 levels were studied. The results revealed low red cell folate levels in 11 out of 25 patients (44%) in group I and 9 out of 16 patients (56%) in group II. The serum vitamin B12 levels were within normal range in both groups. They were defined as having folate deficiency (n = 10), folate deficient erythropoiesis (n = 3) and folate depletion (n = 7). None of them had anemia nor macrocytes. Therefore, folate levels should be investigated in patients with oral lesions and symptoms especially those with risk factors of age, poor nutrition or systemic diseases. When suspected, daily folic acid supplements should be given.
Authors:
K Thongprasom; P Youngnak; V Aneksuk
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Southeast Asian journal of tropical medicine and public health     Volume:  32     ISSN:  0125-1562     ISO Abbreviation:  Southeast Asian J. Trop. Med. Public Health     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2002-04-11     Completed Date:  2002-04-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0266303     Medline TA:  Southeast Asian J Trop Med Public Health     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  643-7     Citation Subset:  IM    
Affiliation:
Department of Oral Medicine, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand. tkobkan@netserv.chula.ac.th
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Folic Acid / blood*
Glossitis / blood*
Humans
Lichen Planus, Oral / blood*
Middle Aged
Stomatitis / blood*
Vitamin B 12 / blood*
Chemical
Reg. No./Substance:
59-30-3/Folic Acid; 68-19-9/Vitamin B 12

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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