Document Detail

Folate fortification: potential impact on folate intake in an older population.
MedLine Citation:
PMID:  11528496     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine the potential impact of different models of folate fortification of Australian foods on the folate intakes of older Australians. DESIGN: Dietary data were collected using a food frequency questionnaire from people attending a population-based health study. SETTING: Two postcode areas west of Sydney, Australia. SUBJECTS: A total of 2895 people aged over 49 y, obtained from a door knock census (79% of 3654 subjects examined). MAIN OUTCOME MEASURES: The folate intake in this population was estimated using four different models: (1) pre-fortification folate values; (2) current voluntary folate fortification in Australia; (3) universal fortification of all foods permitted to add folate, at 25% recommended dietary intake (RDI) per reference serve; and (4) universal fortification of all foods permitted to add folate, at 50% RDI per reference serve. The increased bioavailability of synthetic folic acid (SFA) was included in the analysis. RESULTS: At current voluntary folate fortification, approximately 65% of this population consume 320 microg dietary folate equivalents (DFE) or more per day from diet and supplements, and 0.4% (n=10) consume greater than the recommended upper safety level of 1000 microg from SFA. More than 95% of this older population would be expected to consume more than 320 microg DFE from diet and supplements with universal fortification at 50% of the RDI, and 0.5% (n=14) may consume greater than 1000 microg/day of SFA. CONCLUSIONS: There is unlikely to be a large increase in the proportion of older persons who are likely to consume more than the upper safety level of intake with universal folate fortification. As most of those who currently or are predicted to consume over 1000 microg SFA take supplements containing folic acid, it is highly recommended that vitamin B12 be included in any vitamin supplements containing folate. SPONSORSHIP: This study was supported by the Australian National Health and Medical Research Council (NHMRC).
V M Flood; K L Webb; W Smith; P Mitchell; J M Bantick; R Macintyre; D Sindhusake; G L Rubin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  55     ISSN:  0954-3007     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-08-30     Completed Date:  2001-11-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  793-800     Citation Subset:  IM    
Department of Public Health and Community Medicine, Westmead Hospital, University of Sydney, Sydney, Australia.
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MeSH Terms
Biological Availability
Folic Acid / administration & dosage*,  adverse effects
Food, Fortified / adverse effects
Health Surveys
Middle Aged
Models, Biological
Nutrition Policy
Vitamin B 12 / administration & dosage*
Reg. No./Substance:
59-30-3/Folic Acid; 68-19-9/Vitamin B 12

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