Document Detail

Foetal and maternal hormonal changes preceding normal bovine parturition.
MedLine Citation:
PMID:  576536     Owner:  NLM     Status:  MEDLINE    
Successful chronic cannulation of the foetal posterior vena cava and maternal utero-ovarian and jugular veins in five Jersey cows between days 240 and 260 of gestation enabled changes in plasma hormone levels preceding calving to be monitored. All cows delivered live calves within the expected range of gestation for the breed. Corticosteroids were assayed by competitive protein-binding and prostaglandin F, progesterone, oestrone and oestradiol-17beta by radioimmunoassay. Foetal corticosteroids rose slowly from 5.0 +/- 0.7 ng/ml at 20 days to 9.3 +/- 3.0 ng/ml at 10 days before term, then progressively increased to a mean of 74 ng/ml, though higher concentrations occurred following surgery. Foetal oestrone and oestradiol-17beta concentrations were both less than 50 pg/ml and showed little change toward term. The maternal utero-ovarian oestrogens increased slowly from 20 to 10 days pre-partum and then rose more rapidly reaching peak levels (2.9 +/- 0.6 ng/ml for oestrone and 1.4 +/- 0.3 ng/ml for oestradiol-17beta) 1 to 4 days before delivery. Maternal progesterone concentrations fell towards term, with a rapid decrease over the last 36-48 h before calving when they gradually increased until the last 24 h where was a dramatic rise, reaching peak levels (5.7 +/- 0.6 ng/ml) during labour.
J T Hunter; R J Fairclough; A J Peterson; R A Welch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta endocrinologica     Volume:  84     ISSN:  0001-5598     ISO Abbreviation:  Acta Endocrinol.     Publication Date:  1977 Mar 
Date Detail:
Created Date:  1977-04-15     Completed Date:  1977-04-15     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370312     Medline TA:  Acta Endocrinol (Copenh)     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  653-62     Citation Subset:  IM    
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MeSH Terms
Adrenal Cortex Hormones / blood*
Catheterization / methods
Cattle / physiology*
Estradiol / blood
Estrone / blood
Fetal Blood / analysis*
Gonadal Steroid Hormones / blood*
Labor, Obstetric
Pregnancy, Animal*
Progesterone / blood
Prostaglandins F / blood
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Gonadal Steroid Hormones; 0/Prostaglandins F; 50-28-2/Estradiol; 53-16-7/Estrone; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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