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Focus on granulocyte colony-stimulating factor induced pulmonary toxicity.
MedLine Citation:
PMID:  22265942     Owner:  NLM     Status:  Publisher    
Granulocyte colony-stimulating factor (G-CSF) are frequently used in oncology and haematology practice. Respiratory disturbance has been reported during administration of G-CSF. G-CSF may induce pulmonary toxicity but this fact remains an open debate because of its frequent association with other drugs. The action of these treatments could explain a part of the pulmonary events but not completely. The specific pulmonary effect of the G-CSF is probably underestimated. Most of these pulmonary events occur in association with other risk factors, mainly when a pneumonia occurs during the neutropenia. However, G-CSF are recommended in febrile neutropenia.
Elise Noël-Savina; Renaud Descourt
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-19
Journal Detail:
Title:  Bulletin du cancer     Volume:  -     ISSN:  1769-6917     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0072416     Medline TA:  Bull Cancer     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
CHU de Brest, hôpital Morvan, service d'oncologie thoracique, 5, avenue Foch, 29200 Brest, France.
Vernacular Title:
Le point sur la toxicité pulmonaire des G-CSF.
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