| Focale: study of systolic and diastolic heart failure in a French elderly population. | |
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MedLine Citation:
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PMID: 17399824 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CONTEXT: The epidemic of heart failure (HF) in France has not been fully investigated and data on both the systolic and diastolic forms are limited. OBJECTIVES: To determine the prevalence, aetiology and treatments of both forms in French patients over 65 with HF (NYHA grade II-IV). PARTICIPANTS: Cross-sectional study of 446 patients with HF recruited by 273 randomly selected cardiologists in France, with echocardiography and ECG available for central reading. MAIN MEASUREMENTS: Prevalence of diastolic (DHF) and systolic (SHF) HF using the left ventricular ejection fraction (LVEF). RESULTS: DHF, with a mean LVEF of 57.6+/-8.0%, was reported for 245 (54.9%) patients and SHF, with a mean LVEF of 33.33+/-8.0% was reported for 201 (45.1%) patients. Men were more prone to suffer SHF than DHF whereas for women the reverse was true. As compared to SHF, DHF endsystolic and enddiastolic volumes were smaller, the thickness/radius ratio was greater, with a longer E-wave deceleration time and a shorter peak filling rate. Aetiology and treatments were similar in both types of HF, except for ACE inhibitors and aldosterone antagonists, which were more frequently prescribed in SHF. CONCLUSION: This observational study provides further knowledge of SHF and DHF in outpatients. |
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Authors:
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Olivier Dubourg; Pascal Gueret; Alain Beauchet; Sophie Nisse-Durgeat; Alain Ducardonnet |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-03-30 |
Journal Detail:
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Title: International journal of cardiology Volume: 124 ISSN: 1874-1754 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-02-04 Completed Date: 2008-03-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 188-92 Citation Subset: IM |
Affiliation:
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Hôpital Ambroise Paré, AP-HP Boulogne-Billancourt, Université de Versailles-Saint Quentin en Yvelines, France. olivier.dubourg@apr.aphp.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Distribution Aged Aged, 80 and over Cardiotonic Agents / therapeutic use Cross-Sectional Studies Diastole Echocardiography, Doppler Electrocardiography Female France / epidemiology Geriatric Assessment Heart Failure / diagnosis*, drug therapy, epidemiology* Humans Male Probability Prognosis Risk Assessment Severity of Illness Index Sex Distribution Statistics, Nonparametric Stroke Volume* Survival Analysis Systole Ventricular Dysfunction, Left / diagnosis*, drug therapy, epidemiology* |
| Chemical | |
Reg. No./Substance:
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0/Cardiotonic Agents |
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