| Focal thyroid incidentalomas identified with whole-body FDG-PET warrant further investigation. | |
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MedLine Citation:
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PMID: 22111394 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Fluorodeoxyglucose (FDG) whole body positron emission computed tomography (PET-CT) detects clinically occult malignancy. The aim of this study was to assess the prevalence and significance of focal thyroid 18F - fluorodeoxyglucose uptake. A retrospective review of all patients who had FDG PET-CT examinations, in a single tertiary referral centre was performed. PET scan findings and the final pathological diagnosis were collated. 2105 scans were reviewed. Focal uptake was identified in 35 (1.66%) patients. Final surgical histology was available on eight patients, which confirmed papillary carcinoma in four (20%) patients and lymphoma and metastatic disease in two patients respectively. This gave an overall malignancy rate in focal thyroid uptake of at least 33%. Thyroid incidentalomas occurred with a frequency of 2.13%, with an associated malignancy rate of at least 33% in focal thyroid uptake. The high malignancy rate associated with focal thyroid uptake mandates further investigation in medically fit patients. |
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Authors:
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R S Prichard; M Cotter; D Evoy; D Gibbons; C Collins; E McDermott; S Skehan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Irish medical journal Volume: 104 ISSN: 0332-3102 ISO Abbreviation: Ir Med J Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0430275 Medline TA: Ir Med J Country: Ireland |
Other Details:
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Languages: eng Pagination: 177-9 Citation Subset: IM |
Affiliation:
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St Vincent's University Hospital, Elm Park, Dublin 4 ruthprichard@rcsi.ie |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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