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Focal thyroid incidentalomas identified with whole-body FDG-PET warrant further investigation.
MedLine Citation:
PMID:  22111394     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Fluorodeoxyglucose (FDG) whole body positron emission computed tomography (PET-CT) detects clinically occult malignancy. The aim of this study was to assess the prevalence and significance of focal thyroid 18F - fluorodeoxyglucose uptake. A retrospective review of all patients who had FDG PET-CT examinations, in a single tertiary referral centre was performed. PET scan findings and the final pathological diagnosis were collated. 2105 scans were reviewed. Focal uptake was identified in 35 (1.66%) patients. Final surgical histology was available on eight patients, which confirmed papillary carcinoma in four (20%) patients and lymphoma and metastatic disease in two patients respectively. This gave an overall malignancy rate in focal thyroid uptake of at least 33%. Thyroid incidentalomas occurred with a frequency of 2.13%, with an associated malignancy rate of at least 33% in focal thyroid uptake. The high malignancy rate associated with focal thyroid uptake mandates further investigation in medically fit patients.
Authors:
R S Prichard; M Cotter; D Evoy; D Gibbons; C Collins; E McDermott; S Skehan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Irish medical journal     Volume:  104     ISSN:  0332-3102     ISO Abbreviation:  Ir Med J     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0430275     Medline TA:  Ir Med J     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  177-9     Citation Subset:  IM    
Affiliation:
St Vincent's University Hospital, Elm Park, Dublin 4 ruthprichard@rcsi.ie
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