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Focal segmental glomerulosclerosis in IgA nephropathy: a result of primary podocyte injury?
MedLine Citation:
PMID:  21358653     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Segmental sclerosis is frequently seen in IgA nephropathy and is an adverse prognostic indicator in the Oxford classification. Hill and colleagues have studied patients with IgA nephropathy and show that the segmental sclerotic lesions have features that suggest they are due to primary podocyte injury. They confirm the validity of the Oxford classification in predicting outcome and also show that categorizing the type of FSGS is of prognostic significance, with collapsing and cellular forms having the worst outcome.
Authors:
H Terence Cook
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Kidney international     Volume:  79     ISSN:  1523-1755     ISO Abbreviation:  Kidney Int.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0323470     Medline TA:  Kidney Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  581-3     Citation Subset:  IM    
Affiliation:
Department of Medicine, Imperial College, London, UK.
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