| Focal segmental glomerulosclerosis complicating solitary kidney. | |
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MedLine Citation:
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PMID: 18688570 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 78-year old woman with complicating solitary kidney had nephrotic syndrome. Renal biopsy specimens showed focal segmental glomerulosclerosis (FSGS). First, the patient was treated with angiotensin receptor blocker (ARB) and angiotensin converting enzyme inhibitor (ACEI). Proteinuria decreased from 10 to 6 g/day, but overall the nephrotic syndrome did not improve. Additional treatment with prednisolone and cyclosporine reduced proteinuria to less than 1.0 g/day. We report that combination therapy with ARB, ACEI, prednisolone, and cyclosporine was successful for FSGS complicating solitary kidney. |
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Authors:
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Yoshiyuki Oshiro; Sachio Umena; Masatoshi Noda |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-08-09 |
Journal Detail:
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Title: Clinical and experimental nephrology Volume: 13 ISSN: 1342-1751 ISO Abbreviation: Clin. Exp. Nephrol. Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-02 Completed Date: 2009-03-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9709923 Medline TA: Clin Exp Nephrol Country: Japan |
Other Details:
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Languages: eng Pagination: 81-4 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Kawasaki Medical School Kawasaki Hospital, 2-1-80 Nakasange, Okayama, Japan. y.oshiro@kawasaki-hp.jp. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Angiotensin II Type 1 Receptor Blockers / therapeutic use Angiotensin-Converting Enzyme Inhibitors / therapeutic use Biopsy Cyclosporine / therapeutic use Drug Therapy, Combination Female Glomerulosclerosis, Focal Segmental / drug therapy, etiology*, pathology Glucocorticoids / therapeutic use Humans Immunosuppressive Agents / therapeutic use Kidney Glomerulus / pathology* Nephrectomy / adverse effects* Nephrotic Syndrome / drug therapy, etiology*, pathology Prednisolone / therapeutic use Proteinuria / etiology, pathology Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Angiotensin II Type 1 Receptor Blockers; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Glucocorticoids; 0/Immunosuppressive Agents; 50-24-8/Prednisolone; 59865-13-3/Cyclosporine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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