Document Detail


Focal retrograde amnesia: Extending the clinical syndrome of transient epileptic amnesia.
MedLine Citation:
PMID:  20598890     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 44-year-old woman presented with focal retrograde amnesia and complaints of rapid forgetting in the absence of episodes of transient cognitive disturbance. Her MRI and 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography (FDG-PET) were normal. On standard neuropsychological tests she performed within the normal range although a test of autobiographical memory confirmed impoverished recall especially involving recent life events. The electroencephalograph (EEG) recordings were suggestive of temporal lobe epilepsy but no clear diagnosis was established. After 4 years the patient's recurrent brief episodes of disorientation, suggestive of transient epileptic amnesia (TEA), were corroborated by her sister. This diagnosis was confirmed by an ambulatory EEG that revealed ictal activity. Several important points emerge from this study. Focal retrograde amnesia can be a prodromal symptom of TEA which can precede the full-blown syndrome by several years. Moreover, transient attacks might not be reported if patients live alone. The ictal EEG findings further substantiate the epileptic nature of the syndrome.
Authors:
Michael Hornberger; Armin Mohamed; Laurie Miller; John Watson; Zoe Thayer; John R Hodges
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-07-03
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  17     ISSN:  1532-2653     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-08-16     Completed Date:  2010-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  1319-21     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Prince of Wales Medical Research Institute, Corner of Barker Street and Easy Street, Randwick, New South Wales 2031, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Amnesia, Retrograde / etiology*
Electroencephalography / methods
Epilepsy / complications*
Female
Humans
Mental Recall / physiology
Neuropsychological Tests

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Distinct gene set in two different lineages of ammonia-oxidizing archaea supports the phylum Thaumar...
Next Document:  Modularity in the Hippo signaling pathway.