Document Detail


Focal physiologic fluorodeoxyglucose activity in the gastrointestinal tract is located within the colonic lumen.
MedLine Citation:
PMID:  22240934     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AIM: Physiologic activity of F-fluorodeoxyglucose (FDG) in the intestinal tract occurs frequently in patients undergoing PET/computed tomography (CT) imaging, appearing most often in the colon. The purpose of this study is to determine the localization of the FDG within the colon. We hypothesize that intestinal FDG activity is intraluminal. METHODS: In a prospective Institutional Review Board-approved and Health Insurance Portability and Accountability Act-compliant study, patients with physiologic colonic FDG activity on PET/CT scans were enrolled to undergo repeat imaging 2 h after stimulation of colonic motility with a high-fat meal. RESULTS: We identified 13 patients who had focal FDG activity in their colon during a routine clinical PET/CT scan. After administration of a high-fat meal, 10 patients (77%) demonstrated antegrade movement of FDG along the colon, consistent with luminal clearance. CONCLUSION: Our results suggest that normal physiologic FDG activity within the large intestine, seen on PET/CT scans, is intraluminal.
Authors:
Ke Wang; Yih-Chieh S Chen; Matthew R Palmer; Ilan Tal; Awais Ahmed; Alan C Moss; Gerald M Kolodny
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-11
Journal Detail:
Title:  Nuclear medicine communications     Volume:  -     ISSN:  1473-5628     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8201017     Medline TA:  Nucl Med Commun     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
aDepartment of Radiology, Division of Nuclear Medicine bDepartment of Medicine, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
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