Document Detail


Focal monomorphic ventricular tachycardia as the first manifestation of amyloid cardiomyopathy.
MedLine Citation:
PMID:  20234811     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
52-year-old patient presented with palpitation and well tolerated monomorphic ventricular tachycardia. He had normal echocardiogram and coronary angiogram 3 months prior to presentation. Surface EKG revealed regular wide-complex tachycardia with right bundle branch block morphology and right inferior axis. In conjunction with recent negative cardiac evaluation, this suggested idiopathic focal ventricular tachycardia from anterolateral basal left ventricle. CARTO based activation mapping confirmed the presence of VT focus in that area. Radiofrequency ablation at the site of perfect pacemap resulted in a partial suppression of the focus. Echocardiogram was subsequently performed because of progressive dyspnea. It revealed asymmetrical thickening of posterolateral left ventricle, with delayed enhancement on contrast magnetic resonance imaging. Fine needle aspiration of abdominal fat stained with Congo red confirmed the diagnosis of systemic AL amyloidosis due to IgG lambda-light chain deposition. Consequently, the patient underwent placement of implantable defibrillator and hematopoetic stem cell transplantation. He remains in excellent functional status 18 months after presentation.
Authors:
Srikanth Seethala; Sandeep Jain; N Paul Ohori; Sara Monaco; Joan Lacomis; Frederick Crock; Jan Nemec
Publication Detail:
Type:  Journal Article     Date:  2010-03-05
Journal Detail:
Title:  Indian pacing and electrophysiology journal     Volume:  10     ISSN:  0972-6292     ISO Abbreviation:  Indian Pacing Electrophysiol J     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-17     Completed Date:  2010-05-20     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101157207     Medline TA:  Indian Pacing Electrophysiol J     Country:  India    
Other Details:
Languages:  eng     Pagination:  143-7     Citation Subset:  -    
Affiliation:
Department of Internal Medicine, University of Pittsburgh, 200 Lothrop St, Pittsburgh PA 15213, USA.
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