Document Detail

Foam sclerotherapy for reticular veins and nontruncal varicose veins of the legs: a retrospective review of outcomes and adverse effects.
MedLine Citation:
PMID:  20590709     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Sclerotherapy is the criterion standard of treatment for reticular veins. Foam sclerotherapy is safe and effective, although current guidelines limit the volume of foam used per session. OBJECTIVE: To demonstrate the safety and efficacy of large-volume foam sclerotherapy for the treatment of reticular and nontruncal leg veins. METHODS & MATERIALS: A retrospective review was conducted on all patients undergoing sclerotherapy from 2003 to 2009. Contacted patients graded side effect severity and the degree of vein resolution on a 4-point scale (0-3). The occurrence of cardiovascular or pulmonary events was also recorded. Sclerosant volumes were retrieved from patient records. RESULTS: One thousand one hundred eighty-seven patients underwent sclerotherapy; 419 were successfully contacted of whom 325 had received foam sclerotherapy. The average volume of foam used per session was 16.9 mL. The average rating of adverse events was minimal to mild for all categories including hyperpigmentation (0.35), ulceration (0.06), pain (0.22), and matting or new vessel formation (0.70). The average improvement score was 1.94 (moderate improvement). No serious adverse events occurred. CONCLUSION: Large-volume foam sclerotherapy appears to be safe and effective in the treatment of intracutaneous leg varicosities. Serious adverse events are a rare occurrence, even with sclerosant treatment volumes exceeding current guidelines.
Melanie D Palm; Isabella C Guiha; Mitchel P Goldman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]     Volume:  36 Suppl 2     ISSN:  1524-4725     ISO Abbreviation:  Dermatol Surg     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-01     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504371     Medline TA:  Dermatol Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1026-33     Citation Subset:  IM    
Dermatology/Cosmetic Laser Associates of La Jolla Inc, San Diego, California 92121, USA.
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MeSH Terms
Leg / blood supply*
Middle Aged
Retrospective Studies
Sclerosing Solutions / administration & dosage*,  adverse effects
Sclerotherapy / adverse effects,  methods*
Severity of Illness Index
Treatment Outcome
Varicose Veins / therapy*
Reg. No./Substance:
0/Sclerosing Solutions

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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