Document Detail


Flying spot studies of brain flavoproteins in the gerbil.
MedLine Citation:
PMID:  6114448     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The flying spot fluorometer/reflectometer for flavoprotein (Fp) was used in the present study in order to evaluate energy metabolism in the anesthetized gerbil brain. This model was exposed to various conditions, such as anoxia, spreading depression, and ischemia. The fluorescence and reflected light were analyzed in terms of intensities of histograms, and the fractional changes were calculated and compared between the metabolic states. The results show that under various conditions, the fluorescence of Fp changed together with the reflectance change, and the net mitochondrial change was not always clear. The results presented in the study are in good agreement with the previously-published results.
Authors:
B R Silberstein; A Mayevsky; B Chance
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Neurological research     Volume:  2     ISSN:  0161-6412     ISO Abbreviation:  Neurol. Res.     Publication Date:  1980  
Date Detail:
Created Date:  1981-09-25     Completed Date:  1981-09-25     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7905298     Medline TA:  Neurol Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  19-34     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain Ischemia / metabolism
Cerebral Cortex / metabolism*
Cortical Spreading Depression
Female
Flavoproteins / metabolism*
Fluorometry
Gerbillinae / metabolism*
Hypoxia, Brain / metabolism
Male
Grant Support
ID/Acronym/Agency:
HL 18708/HL/NHLBI NIH HHS; NINCDS 10939/DS/DS NIH HHS
Chemical
Reg. No./Substance:
0/Flavoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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