Document Detail

Flurandrenolide tape.
MedLine Citation:
PMID:  4648569     Owner:  NLM     Status:  MEDLINE    
The effectiveness, mechanism of action and safety of copper in IUDs are briefly reviewed. In 1 study, 18.3 pregnancies occurred per 100 women during the 1st year of use of a T-shaped IUD whereas with a copper wire wound around the device, only 2 pregnancies occurred. The mechanism of action may be related to infiltration of polymorphonuclear leukocytes in the uterine mucosa or to a toxic effect of copper on the embryo. The dissolved copper ions appear to be the actual contraceptive agent since a large fraction of copper wire placed in a human uterus dis appears within a year and metals with low solubility are not effective. The duration of effectiveness and the safety of these experimental devices have not been established.
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Medical letter on drugs and therapeutics     Volume:  14     ISSN:  0025-732X     ISO Abbreviation:  Med Lett Drugs Ther     Publication Date:  1972 Oct 
Date Detail:
Created Date:  1973-03-21     Completed Date:  1973-03-21     Revised Date:  2010-09-17    
Medline Journal Info:
Nlm Unique ID:  2985240R     Medline TA:  Med Lett Drugs Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  83     Citation Subset:  AIM; IM; J    
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MeSH Terms
Costs and Cost Analysis
Flurandrenolone / administration & dosage*,  adverse effects
Occlusive Dressings* / adverse effects
Skin Diseases / chemically induced,  drug therapy*,  etiology
Reg. No./Substance:
0/Polyethylenes; 1524-88-5/Flurandrenolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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