| Fluphenazine decanoate, oral fluphenazine, and placebo in treatment of remitted schizophrenics. II. Rating scale data. | |
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MedLine Citation:
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PMID: 199129 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study of patients with remitted chronic schizophrenia in an aftercare clinic was designed to test whether such patients require maintenance antipsychotic medication. A previous report showed that the group receiving active medication, fluphenazine decanoate and oral fluphenazine, had far fewer relapses; but the former group had a high incidence of akinesia. This present report presents rating scale data substantiating these two findings: (1) patients terminated on clinical grounds because of a schizophrenic relapse showed rating scale changes consistent with that diagnosis; and (2) the patients removed due to severe akinesia showed a worsening on items selected a priori to measure akinesia, and when compared to survivors on the same items, showed significant differences--thus confirming our clinical judgments. |
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Authors:
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A Rifkin; F Quitkin; D F Klein |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Archives of general psychiatry Volume: 34 ISSN: 0003-990X ISO Abbreviation: Arch. Gen. Psychiatry Publication Date: 1977 Oct |
Date Detail:
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Created Date: 1977-11-30 Completed Date: 1977-11-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372435 Medline TA: Arch Gen Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1215-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Aftercare* Basal Ganglia Diseases / chemically induced Chronic Disease Double-Blind Method Fluphenazine / administration & dosage*, therapeutic use Humans Injections Placebos Psychiatric Status Rating Scales Remission, Spontaneous Schizophrenia / prevention & control* |
| Chemical | |
Reg. No./Substance:
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0/Placebos; 69-23-8/Fluphenazine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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