| Fluorous Supported Modular Synthesis of Heparan Sulfate Oligosaccharides. | |
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MedLine Citation:
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PMID: 23293947 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The modular synthesis of heparan sulfate fragments is greatly facilitated by employing an anomeric aminopentyl linker protected by a benzyloxycarbonyl group modified by a perfluorodecyl tag, which made it possible to purify highly polar intermediates by fluorous solid phase extraction. This tagging methodology made it also possible to perform repeated glycosylations to drive reactions to completion. |
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Authors:
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Chengli Zong; Andre Venot; Omkar Dhamale; Geert-Jan Boons |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-8 |
Journal Detail:
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Title: Organic letters Volume: - ISSN: 1523-7052 ISO Abbreviation: Org. Lett. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Complex Carbohydrate Research Center, The University of Georgia , 315 Riverbend Road, Athens, Georgia 30602, United States, and Department of Chemistry, The University of Georgia , Athens, Georgia, Georgia 30602, United States. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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