| Fluorosugars: synthesis of the 2,3,4-trideoxy-2,3,4-trifluoro hexose analogues of D-glucose and D-altrose and assessment of their erythrocyte transmembrane transport. | |
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MedLine Citation:
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PMID: 20532277 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The 2,3,4-trideoxy-2,3,4-trifluoro hexose analogues of d-glucose and d-altrose were prepared and characterised and these novel sugar analogues were explored by 2D-(19)F-EXSY NMR for their potential to cross erythrocyte (red blood cell) membranes, by comparison with the well known capacity of erythrocytes to transport d-glucose. |
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Authors:
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Stefano Bresciani; Tomas Lebl; Alexandra M Z Slawin; David O'Hagan |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-06-07 |
Journal Detail:
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Title: Chemical communications (Cambridge, England) Volume: 46 ISSN: 1364-548X ISO Abbreviation: Chem. Commun. (Camb.) Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-20 Completed Date: 2010-10-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610838 Medline TA: Chem Commun (Camb) Country: England |
Other Details:
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Languages: eng Pagination: 5434-6 Citation Subset: IM |
Affiliation:
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University of St Andrews, School of Chemistry and Centre for Biomolecular Sciences, North Haugh, St Andrews, Fife, KY16 9ST, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cell Membrane Permeability Crystallography, X-Ray Erythrocytes / metabolism* Glucose / chemical synthesis, chemistry*, metabolism* Halogenation* Hexoses / chemical synthesis, chemistry*, metabolism* Humans Models, Molecular Nuclear Magnetic Resonance, Biomolecular |
| Chemical | |
Reg. No./Substance:
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0/Hexoses; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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