Document Detail

Fluoroquinolone-associated bilateral patellar tendon rupture: a case report and review of the literature.
MedLine Citation:
PMID:  20572481     Owner:  NLM     Status:  MEDLINE    
Single series case reports have described bilateral traumatic patellar tendon ruptures, and less frequently, with little or no trauma. Patellar tendon rupture most often occurs in patients younger than 40 years old and is commonly precipitated by a sudden, significant eccentric contraction. Patellar tendon ruptures are uncommon in those older than 40 years of age, but when they occur, may indicate an underlying systemic disorder. Corticosteroid injections, rheumatic disease, metabolic disorders, and fluoroquinolone use have all been associated with increased risk of tendon rupture. While the Achilles tendon is the most commonly affected by fluoroquinolone use, cases involving the rotator cuff, biceps, wrist extensors, and quadriceps tendon among others, have been described. A case is presented of a 43-year-old man without pre-existing medical comorbidities who sustained atraumatic bilateral patellar tendon ruptures following a treatment course of fluoroquinolone medication.
Daniel J Stinner; Justin D Orr; Joseph R Hsu
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Military medicine     Volume:  175     ISSN:  0026-4075     ISO Abbreviation:  Mil Med     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-24     Completed Date:  2010-07-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984771R     Medline TA:  Mil Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  457-9     Citation Subset:  IM    
United States Institute of Surgical Research, 3400 Rawley E. Chambers Avenue, Fort Sam Houston, TX 78234, USA.
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MeSH Terms
Anti-Bacterial Agents / adverse effects*,  therapeutic use
Ciprofloxacin / adverse effects,  therapeutic use
Fluoroquinolones / adverse effects*,  therapeutic use
Follow-Up Studies
Musculoskeletal Diseases / chemically induced*,  diagnosis,  surgery
Patellar Ligament / drug effects*,  surgery
Respiratory Tract Infections / drug therapy
Rupture, Spontaneous / chemically induced
Suture Techniques
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Fluoroquinolones; 85721-33-1/Ciprofloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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