Document Detail

Fluoride - is it capable of fighting old and new dental diseases? An overview of existing fluoride compounds and their clinical applications.
MedLine Citation:
PMID:  11359049     Owner:  NLM     Status:  MEDLINE    
Since researchers first became aware of the anticaries action of fluoride, they have been investigating the effect of this preventive agent in inhibiting or arresting caries development. Many forms of systemic or topical fluoride have been studied and tested for clinical application. Water, salt, milk fluoridation and the use of fluoride supplements were introduced for systemic fluoridation mainly using sodium fluoride. Solutions, gels, toothpastes and rinses of sodium fluoride, stannous fluoride, amine fluorides, acidulated phosphate fluoride and monofluorophosphate were used for topical fluoridation. More recently nonaqueous fluoride varnishes in an alcoholic solution of natural resins and difluorosilane agents in a polyurethane matrix were introduced. Although all of these fluoridation methods have a caries-preventive action, these benefits and the ease of application is variable. As fluoride is a key component of oral health promotion a coordinated approach on a community and individual basis seems to be needed to maximize the cost-benefit ratio of prevention.
E Brambilla
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Caries research     Volume:  35 Suppl 1     ISSN:  0008-6568     ISO Abbreviation:  Caries Res.     Publication Date:  2001  
Date Detail:
Created Date:  2001-05-18     Completed Date:  2001-08-16     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0103374     Medline TA:  Caries Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  6-9     Citation Subset:  D; IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel.
Department of Pediatric Dentistry, University of Milan, Italy.
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MeSH Terms
Cariostatic Agents / administration & dosage,  economics,  therapeutic use*
Cost-Benefit Analysis
Delayed-Action Preparations
Dental Caries / prevention & control*
Fluorides / administration & dosage,  economics,  therapeutic use*
Fluorides, Topical / administration & dosage,  economics,  therapeutic use
Mouthwashes / therapeutic use
Sodium Chloride, Dietary / administration & dosage
Toothpaste / therapeutic use
Reg. No./Substance:
0/Cariostatic Agents; 0/Delayed-Action Preparations; 0/Fluorides; 0/Fluorides, Topical; 0/Gels; 0/Mouthwashes; 0/Polyurethanes; 0/Silanes; 0/Sodium Chloride, Dietary; 0/Toothpaste

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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