Document Detail

Fluoride-containing gels, mouth rinses and varnishes: an update of evidence of efficacy.
MedLine Citation:
PMID:  19772845     Owner:  NLM     Status:  MEDLINE    
AIM: This was to review and update knowledge from presently available systematic reviews of clinical trials on the effect of fluoride containing gels, mouth rinses and varnishes. METHODS: The review was based on an electronic search of three data bases (PubMed 2000 to 2008, EMBASE 2000- 2009, Cochrane 2000-2008) using a search profile similar to that used in previous Cochrane reviews on the caries-preventive effect of topical fluoride methods. Only randomized and semi-randomized trials were included. RESULTS: Four new studies were identified on fluoride-containing gels, one on fluoride mouth rinses and four on fluoride-containing varnishes. Prevented fractions obtained in the permanent dentition were consistent with the estimates found in previous reviews, while the effect obtained on caries in the primary dentition remains uncertain. The only study that compared the effect of different fluoride compounds, could not find any difference. CONCLUSIONS: The effect of the three methods on caries in the permanent dentition is well described, while the effect on caries in the primary dentition remains to be determined. The effect of choice of fluoride compound is also not known.
S Poulsen
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry     Volume:  10     ISSN:  1818-6300     ISO Abbreviation:  Eur Arch Paediatr Dent     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-23     Completed Date:  2010-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101277157     Medline TA:  Eur Arch Paediatr Dent     Country:  England    
Other Details:
Languages:  eng     Pagination:  157-61     Citation Subset:  D; IM    
Department of Pediatric Dentistry, School of Dentistry, Faculty of Health Sciences, Aarhus University, Aarhus C, Denmark.
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MeSH Terms
Cariostatic Agents / therapeutic use*
Dental Caries / prevention & control*
Fluorides / therapeutic use*
Fluorides, Topical / therapeutic use*
Mouthwashes / therapeutic use*
Randomized Controlled Trials as Topic
Tooth / drug effects
Tooth, Deciduous / drug effects
Reg. No./Substance:
0/Cariostatic Agents; 0/Fluorides; 0/Fluorides, Topical; 0/Gels; 0/Mouthwashes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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