| Fluoride concentration and pH of pediatric medicines regularly and long-term used by children. | |
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MedLine Citation:
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PMID: 21196893 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: Our aim in this study was to determine the fluoride concentration and pH of 71 pediatric medicines regularly and long-term used by children. STUDY DESIGN: The fluoride concentration was evaluated by selective electrode of fluoride (Orion). The pH was confronted using specific electrode (Orion) coupled to a potentiometer (Orion). The analyses were accomplished in duplicate. Pearson 's correlation and Kruskal-Wallis test were used. P-values below 5% were considered statistically significant. RESULTS: Medicine pH averages±SD varied from 2.3±0.01 to up 10.6±0.02. Values below critical pH were observed in 42.25% (n=30) of presentations, with 25.35% (n=18) below 4.5 pH. Most medicines (84.5%) presented fluoride concentration below 0.05 mg/L. CONCLUSIONS: Among the pediatric medicines evaluated, this study has showed that 2-4 times-a-day posology and syrup formulations presented lowest pH and fluoride concentration, resulting in factors that predict highest cariogenic and erosive potential. |
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Authors:
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Isabela-Albuquerque Passos; Cláudia-Helena-Soares de M Freitas; Fábio-Correia Sampaio |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2011-05-01 |
Journal Detail:
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Title: Medicina oral, patología oral y cirugía bucal Volume: 16 ISSN: 1698-6946 ISO Abbreviation: Med Oral Patol Oral Cir Bucal Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-05-02 Completed Date: 2011-09-01 Revised Date: 2011-09-14 |
Medline Journal Info:
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Nlm Unique ID: 101231694 Medline TA: Med Oral Patol Oral Cir Bucal Country: Spain |
Other Details:
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Languages: eng Pagination: e459-62 Citation Subset: D; IM |
Affiliation:
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Federal University of Paraíba, Rua José Firmino Ferreira, 1060/ 103, Bancários, João Pessoa, Paraíba, Brazil. isabelaapassos@yahoo.com.br |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child Fluorides / analysis* Humans Hydrogen-Ion Concentration Pharmaceutical Preparations / chemistry* Time Factors Tooth / drug effects |
| Chemical | |
Reg. No./Substance:
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0/Fluorides; 0/Pharmaceutical Preparations |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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