Document Detail


Fluorescent polymer-based post-translational differentiation and subtyping of breast cancer cells.
MedLine Citation:
PMID:  23061092     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Herein, we report the application of synthesized fluorescent, water soluble polymers for post-translational subtyping and differentiation of breast cancer cells in vitro. The fluorescence emission spectra from these polymers were modulated differently in the presence of conditioned cell culture media from various breast cancer cells. These polymers differentiate at a post-translation level possibly due to their ability to interact with extracellular enzymes that are over-expressed in cancerous conditions.
Authors:
Michael D Scott; Rinku Dutta; Manas K Haldar; Anil Wagh; Thomas R Gustad; Benedict Law; Daniel L Friesner; Sanku Mallik
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-12
Journal Detail:
Title:  The Analyst     Volume:  -     ISSN:  1364-5528     ISO Abbreviation:  Analyst     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372652     Medline TA:  Analyst     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58108-6050, USA. sanku.mallik@ndsu.edu.
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