Document Detail

Fluorescent antinuclear antibody and anti-double-stranded DNA antibody testing: a four years experience.
MedLine Citation:
PMID:  9361484     Owner:  NLM     Status:  MEDLINE    
Fluorescent antinuclear antibody test (FANA) and anti-double stranded deoxytribonucleic acid (dsDNA) antibody testing is an integral part of the evaluation of the patients who are suspected of having connective tissue disease. We tested 2,140 serum samples for FANA and 1,460 serum samples for anti-dsDNA antibodies. Of 2,140 serum samples tested for FANA, 492 (23%) yielded a positive result (titre of 1:80 or greater) and of 1,460 serum samples tested for anti-dsDNA, 69 (4.7%) yielded positive results. Highest number (n = 27) of serum samples positive for anti-dsDNA antibodies were found in serum samples that were positive for FANA test at a titre of 1:1280 or greater. In conclusion, FANA test can be used as an initial screening test for connective tissue/autoimmune disorders.
F Anwer; A M Abou-Azama; A Mandourah; M Borja; R Soriano; S G Mercado
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  47     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1998-01-21     Completed Date:  1998-01-21     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  PAKISTAN    
Other Details:
Languages:  eng     Pagination:  226-8     Citation Subset:  IM    
Department of Laboratory Medicine, Al-Hada Armed Forces Hospital, Taif, Saudi Arabia.
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MeSH Terms
Antibodies, Antinuclear / blood*
Autoantibodies / blood*
Connective Tissue Diseases / diagnosis*
DNA / blood*
Fluorescent Antibody Technique*
Reg. No./Substance:
0/Antibodies, Antinuclear; 0/Autoantibodies; 9007-49-2/DNA

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