| Fluorescence resonance energy transfer as a structural tool for nucleic acids. | |
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MedLine Citation:
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PMID: 11006537 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fluorescence resonance energy transfer is a spectroscopic method that provides distance information on macromolecules in solution in the range 20-80 A. It is particularly suited to the analysis of the global structure of nucleic acids because the long-range distance information provides constraints when modelling these important structures. The application of fluorescence resonance energy transfer to nucleic acid structure has seen a resurgence of interest in the past decade, which continues to increase. An especially exciting development is the recent extension to single-molecule studies. |
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Authors:
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D M Lilley; T J Wilson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Current opinion in chemical biology Volume: 4 ISSN: 1367-5931 ISO Abbreviation: Curr Opin Chem Biol Publication Date: 2000 Oct |
Date Detail:
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Created Date: 2000-11-07 Completed Date: 2000-11-07 Revised Date: 2009-08-25 |
Medline Journal Info:
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Nlm Unique ID: 9811312 Medline TA: Curr Opin Chem Biol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 507-17 Citation Subset: IM |
Affiliation:
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CRC Nucleic Acid Structure Research Group, Department of Biochemistry, The University of Dundee, Dundee DD1 4HN, UK. dmjilley@bad.dundee.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Nucleic Acid Conformation* Nucleic Acids / chemistry* Spectrometry, Fluorescence |
| Chemical | |
Reg. No./Substance:
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0/Nucleic Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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