| Fluorescein angiography and retinal vascular development in premature infants. | |
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MedLine Citation:
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PMID: 23016619 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective: To investigate the role of fluorescein angiography (FA) in the management of retinopathy of prematurity (ROP) in preterm newborns. Methods: An observational case series of 13 extremely low birth weight infants. From September 2009 to March 2010, 13 newborn infants with a gestational age <29 weeks end/or birth weight <1000 g underwent serial fluorescein angiography with RetCam (Clarity, Pleasanton, CA) every 2 weeks. The fluorescein angiograms were examined to optimize the timing of diagnosis of ROP and to investigate development of retinal and choroidal vascularization. Results: There were no side effects related to FA. Variable features of retinal and choroidal circulation in preterm infants with a high risk of developing ROP were noted. FA allows vessels branching at the junction between vascular and avascular retina (V-Av junction) to be viewed easily and shows the ROP findings that sometimes cannot be seen by indirect ophthalmoscopy. Dye leakage is the most significant sign of progression to severe ROP or the need for surgery in newborn babies with ROP. Conclusions: RetCam-assisted intravenous FA is safe and allows a more objective assessment of the ROP stage and zone. |
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Authors:
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Purcaro Velia; Baldascino Antonio; Papacci Patrizia; Giannantonio Carmen; Molisso Anna; Molle Fernando; Lepore Domenico; Romagnoli Costantino |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: 25 Suppl 3 ISSN: 1476-4954 ISO Abbreviation: J. Matern. Fetal. Neonatal. Med. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-09-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: England |
Other Details:
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Languages: eng Pagination: 53-6 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, Division of Neonatology, Catholic University of Rome , Rome , Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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