| Flunarizine i.v. after cardiac arrest (FLUNA-study): study design and organisational aspects of a double-blind, placebo-controlled randomized study. | |
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MedLine Citation:
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PMID: 2551008 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To investigate the cerebro-protective effect of flunarizine i.v. in patients successfully resuscitated from ventricular fibrillation outside hospital, a double-blind, placebo-controlled randomized study was started in February 1988 in West-Berlin with all eight Mobile Intensive Care Units and ten major hospitals participating. Start of treatment was in the patient's home immediately after restoration of stable circulatory conditions. Primary endpoints reduction of mortality due to hypoxic brain damage and more rapid improvement after cardiac arrest and resuscitation. Inclusion criteria men and women without age limit, ventricular fibrillation prior to or upon arrival of a MICU, primarily successful cardiac resuscitation with continuing unconsciousness. Recruitment of patients will end January 31st, 1990. An inclusion of about 500 patients is expected. |
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Authors:
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R Schröder; |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Resuscitation Volume: 17 Suppl ISSN: 0300-9572 ISO Abbreviation: Resuscitation Publication Date: 1989 |
Date Detail:
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Created Date: 1989-10-20 Completed Date: 1989-10-20 Revised Date: 2009-08-25 |
Medline Journal Info:
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Nlm Unique ID: 0332173 Medline TA: Resuscitation Country: IRELAND |
Other Details:
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Languages: eng Pagination: S121-7; discussion S199-206 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Clinical Trials as Topic Double-Blind Method Flunarizine / therapeutic use* Heart Arrest / drug therapy* Humans Injections, Intravenous Medical Records Research Design |
| Chemical | |
Reg. No./Substance:
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52468-60-7/Flunarizine |
| Comments/Corrections | |
Erratum In:
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Resuscitation 1990 Apr;19(2):87 Note: Schröder, R [removed] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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