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Fluid volume changes and LBNP response after simulated weightlessness with varied oral sodium supply.
MedLine Citation:
PMID:  15002501     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
There is evidence on body fluid volume effects of head-down tilt bed rest and altered oral sodium supply, but the combined impact of both has not been investigated in detail. We therefore studied circulatory adaptation to 8 days -6 degrees head down bed rest (HDBR) with different levels (-140 to -430 mM/d) of oral sodium load (SL). We expected decreased extracellular volume and increased aldosterone and PRA levels with low sodium load, and hypothesized that these effects get exaggerated with additional HDBR, also influencing lower body suction (LBNP) responses. Variations in sodium status seem to influence plasma but not interstitial volume, confirming recent results of another group who used different experimental conditions.
Authors:
H Hinghofer-Szalkay; A Rossler; H Scharfetter; K Pliz; Z Laszlo
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology     Volume:  9     ISSN:  1077-9248     ISO Abbreviation:  J Gravit Physiol     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2004-03-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9437868     Medline TA:  J Gravit Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  P99-100     Citation Subset:  IM    
Affiliation:
Institute for Adaptive and Spaceflight Physiology, Graz, Austia. www.asm.at/iap
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