Document Detail

Fluid-structure interaction within realistic three-dimensional models of the aneurysmatic aorta as a guidance to assess the risk of rupture of the aneurysm.
MedLine Citation:
PMID:  11755809     Owner:  NLM     Status:  MEDLINE    
Abdominal aortic aneurysm (AAA) disease is a degenerating process whose ultimate event is the rupture of the vessel wall. Rupture occurs when the stresses acting on the wall rise above the strength of the AAA wall tissue. The complex mechanical interaction between blood flow and wall dynamics in a three dimensional custom model of a patient AAA was studied by means of computational coupled fluid-structure interaction analysis. Real 3D AAA geometry is obtained from CT scans image processing. The results provide a quantitative local evaluation of the stresses due to local structural and fluid dynamic conditions. The method accounts for the complex geometry of the aneurysm, the presence of a thrombus and the interaction between solid and fluid. A proven clinical efficacy may promote the method as a tool to determine factual aneurysm risk of rupture and aid the surgeon to refer elective surgery patients.
E S Di Martino; G Guadagni; A Fumero; G Ballerini; R Spirito; P Biglioli; A Redaelli
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Medical engineering & physics     Volume:  23     ISSN:  1350-4533     ISO Abbreviation:  Med Eng Phys     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-12-28     Completed Date:  2002-02-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9422753     Medline TA:  Med Eng Phys     Country:  England    
Other Details:
Languages:  eng     Pagination:  647-55     Citation Subset:  IM    
Department of Bioengineering, Politecnico of Milano, Milan, Italy.
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MeSH Terms
Aorta, Abdominal / physiopathology*,  radiography
Aortic Aneurysm, Abdominal / physiopathology*,  radiography
Aortic Rupture / physiopathology*
Blood Flow Velocity
Computer Simulation*
Image Processing, Computer-Assisted
Imaging, Three-Dimensional
Stress, Mechanical
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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