| Fluid-structure interaction within realistic three-dimensional models of the aneurysmatic aorta as a guidance to assess the risk of rupture of the aneurysm. | |
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MedLine Citation:
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PMID: 11755809 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Abdominal aortic aneurysm (AAA) disease is a degenerating process whose ultimate event is the rupture of the vessel wall. Rupture occurs when the stresses acting on the wall rise above the strength of the AAA wall tissue. The complex mechanical interaction between blood flow and wall dynamics in a three dimensional custom model of a patient AAA was studied by means of computational coupled fluid-structure interaction analysis. Real 3D AAA geometry is obtained from CT scans image processing. The results provide a quantitative local evaluation of the stresses due to local structural and fluid dynamic conditions. The method accounts for the complex geometry of the aneurysm, the presence of a thrombus and the interaction between solid and fluid. A proven clinical efficacy may promote the method as a tool to determine factual aneurysm risk of rupture and aid the surgeon to refer elective surgery patients. |
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Authors:
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E S Di Martino; G Guadagni; A Fumero; G Ballerini; R Spirito; P Biglioli; A Redaelli |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Medical engineering & physics Volume: 23 ISSN: 1350-4533 ISO Abbreviation: Med Eng Phys Publication Date: 2001 Nov |
Date Detail:
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Created Date: 2001-12-28 Completed Date: 2002-02-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9422753 Medline TA: Med Eng Phys Country: England |
Other Details:
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Languages: eng Pagination: 647-55 Citation Subset: IM |
Affiliation:
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Department of Bioengineering, Politecnico of Milano, Milan, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aorta, Abdominal
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physiopathology*,
radiography Aortic Aneurysm, Abdominal / physiopathology*, radiography Aortic Rupture / physiopathology* Blood Flow Velocity Computer Simulation* Hemorheology* Humans Image Processing, Computer-Assisted Imaging, Three-Dimensional Risk Stress, Mechanical Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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