Document Detail


Fluid-structure interaction based study on the physiological factors affecting the behaviors of stented and non-stented thoracic aortic aneurysms.
MedLine Citation:
PMID:  21722905     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Endovascular aneurysm repair (EVAR) is considered as a promising alternative technique for the treatment of aortic aneurysm. However, complications often occur after EVAR. In this paper, the influence of the physiological factors on the biomechanical behaviors of stented and non-stented thoracic aortic aneurysm (TAA) were presented. Representative TAA models with different intraluminal thrombus (ILT) volume before and after stent-graft (SG) implantation were built. Fluid-structure interaction effect was taken into account. The relative sliding between the SG wall and the aortic wall was allowed. Results showed that the cardiac cycle and ILT volume should be given much more consideration than previously thought in future investigations on TAA compliance. The time-averaged longitudinal displacement of SG necks were not uniformly distributed along circumferential direction of the aortic wall. Drag force increased with the increase of the cardiac cycle and decreased with the decrease of ILT volume. Computational results of TAA wall stress, sac and lumen pressure indicated that patient with faster heart rate might be at great risk of aneurysm rupture. The stress absorption effect of the SG was influenced by both ILT and cardiac cycle, which was also found to have strong impact on flow pattern. We believe that this study will bring new insights into further researches on the relevant issues and provide mechanics-based implications for clinical management of EVAR for TAA patient.
Authors:
Xiaohong Wang; Xiaoyang Li
Related Documents :
1519195 - Surgical closed pulmonary valvotomy for critical pulmonary stenosis: implications for t...
17729165 - Increased expression of nuclear nf-kappab after coronary artery balloon injury can be i...
11108695 - Transcatheter atrial septal defect occlusion in piglets by balloon detachable devices.
9857895 - Adventitial vasa vasorum in balloon-injured coronary arteries: visualization and quanti...
2354985 - Percutaneous transluminal coronary angioplasty using kissing balloon technique in the l...
7041795 - The fate of circulating amines within the pulmonary circulation.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-29
Journal Detail:
Title:  Journal of biomechanics     Volume:  -     ISSN:  1873-2380     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-7-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0157375     Medline TA:  J Biomech     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Biomechanical Research Laboratory, College of Mechanical Engineering and Applied Electronics Technology, Beijing University of Technology, No.100 Pingleyuan, Chaoyang District, Beijing, PR China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Tumor necrosis factor-? converting enzyme is a key mediator of abdominal aortic aneurysm development...
Next Document:  The human proximal femur behaves linearly elastic up to failure under physiological loading conditio...