Document Detail

Fluid resuscitation of the thermally injured patient.
MedLine Citation:
PMID:  19793552     Owner:  NLM     Status:  MEDLINE    
Increased capillary permeability and reduced plasma colloid osmotic pressure following burn injury result in hypovolemia and development of edema in the burn and nonburn tissues. Replenishment of the intravascular deficit with crystalloid fluid has been the mainstay of resuscitation for the better part of four decades. A progressive but as yet unexplained trend toward provision of resuscitation volumes well in excess of those predicted by the Parkland formula, associated with numerous edema-related complications, has been repeatedly observed recently. Correction of this phenomenon, called fluid creep, will likely revolve around several strategies, which may include tighter control of titration, re-emergence of colloids and hypertonic salt solutions, and possibly the use of adjunctive markers of resuscitation other than urinary output.
Robert Cartotto
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinics in plastic surgery     Volume:  36     ISSN:  1558-0504     ISO Abbreviation:  Clin Plast Surg     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-01     Completed Date:  2009-12-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0424767     Medline TA:  Clin Plast Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  569-81     Citation Subset:  IM    
Department of Surgery, University of Toronto, Canada.
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MeSH Terms
Burns / physiopathology*,  therapy*
Fluid Therapy / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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