Document Detail


Fluid replacement following dehydration reduces oxidative stress during recovery.
MedLine Citation:
PMID:  19344695     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To investigate the effects of hydration status on oxidative DNA damage and exercise performance, 10 subjects ran on a treadmill until exhaustion at 80% VO(2max) during four different trials [control (C), 3% dehydration (D), 3% dehydration+water (W) or 3% dehydration+sports drink (S)]. Dehydration significantly decreased exercise time to exhaustion (D<C and S). Plasma MDA levels were significantly higher at pre-exercise in D than C. Plasma TAS was significantly lower at pre-exercise in C and S than in D, and was significantly lower in S than D at 60min of recovery. Dehydration significantly increased oxidative DNA damage during exercise, but fluid replacement with water or sports drink alleviated it equally. These results suggest that (1) dehydration impairs exercise performance and increases DNA damage during exercise to exhaustion; and (2) fluid replacement prolongs exercise endurance and attenuates DNA damage.
Authors:
Il-Young Paik; Myung-Hyun Jeong; Hwa-Eun Jin; Young-Il Kim; Ah-Ram Suh; Su-Youn Cho; Hee-Tae Roh; Chan-Ho Jin; Sang-Hoon Suh
Related Documents :
8941545 - Exercise causes blood glutathione oxidation in chronic obstructive pulmonary disease: p...
6339215 - 5-nitroacenaphthene: a newly recognized role for the nitro function in mutagenicity.
7675835 - Responses of antioxidant system to acute and trained exercise in rat heart subcellular ...
15522705 - The oxidative stress in response to routine incremental cycling exercise in healthy sed...
22506725 - Effects of firefighters' self-contained breathing apparatus' weight and its harness des...
8837565 - Role of adenosine in pathogenesis of syndrome x: assessment with coronary hemodynamic m...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-04-01
Journal Detail:
Title:  Biochemical and biophysical research communications     Volume:  383     ISSN:  1090-2104     ISO Abbreviation:  Biochem. Biophys. Res. Commun.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-27     Completed Date:  2009-05-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372516     Medline TA:  Biochem Biophys Res Commun     Country:  United States    
Other Details:
Languages:  eng     Pagination:  103-7     Citation Subset:  IM    
Affiliation:
Department of Physical Education, Yonsei University, Shinchon-Dong, Seodaemun-Gu, Seoul, South Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Antioxidants / analysis
DNA Damage / drug effects
Dehydration / blood,  physiopathology*
Exercise
Humans
Lymphocytes / drug effects,  metabolism
Male
Malondialdehyde / blood
Oxidative Stress / drug effects*
Water / administration & dosage*
Young Adult
Chemical
Reg. No./Substance:
0/Antioxidants; 542-78-9/Malondialdehyde; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Purification of cytoplasmic actin by affinity chromatography using the C-terminal half of gelsolin.
Next Document:  Brain-derived neurotrophic factor and electrophysiological properties of voltage-gated ion channels ...