Document Detail

Fluid overload and acute kidney injury.
MedLine Citation:
PMID:  20955269     Owner:  NLM     Status:  In-Process    
Acute kidney injury is commonly encountered in critically ill patients, and is associated with worse outcomes. Fluid therapy is a key component in the management of these patients, often leading to fluid overload, especially in the setting of septic acute kidney injury. Emerging data overwhelmingly suggest that fluid overload in these patients may be associated with adverse outcomes. Management of such patients should include a strategy of early guided resuscitation, followed by careful assessment of fluid status, and early initiation of renal replacement therapy as soon as it is deemed safe, aiming for a neutral or negative fluid balance. This review will focus on the pathophysiological link between fluid overload and acute kidney injury, mechanisms of organ dysfunction in fluid overload, and strategies for management.
Preethi Yerram; Poorna R Karuparthi; Madhukar Misra
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hemodialysis international. International Symposium on Home Hemodialysis     Volume:  14     ISSN:  1542-4758     ISO Abbreviation:  Hemodial Int     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101093910     Medline TA:  Hemodial Int     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  348-54     Citation Subset:  IM    
Copyright Information:
© 2010 The Authors. Hemodialysis International © 2010 International Society for Hemodialysis.
Department of Internal Medicine, Division of Nephrology, University of Missouri-Columbia, Columbia, Missouri, USA.
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