Document Detail

Fluid movement across the blood-retinal barrier: a review of studies by vitreous fluorophotometry.
MedLine Citation:
PMID:  2214357     Owner:  NLM     Status:  MEDLINE    
Vitreous fluorophotometry was used to study the fluid movement across the blood-retinal barrier. The effect of plasma osmolality and intraocular pressure on the movement of the fluorescent tracer confirmed the interaction between the tracers and the fluid flow across the blood-retinal barrier. The measurement of outward and inward permeabilities to carboxyfluorescein revealed the existence of a posteriorly directed fluid flow in the vitreous cavity of cynomolgus monkey eyes with retinal detachment. Fluid movement across the blood-retinal barrier was shown to be inhibited by furosemide and enhanced by acetazolamide. Furthermore, vitreous fluorophotometry proved to be useful in estimating the in vivo fluid dynamics in the vitreous and across the human retina.
S Tsuboi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Japanese journal of ophthalmology     Volume:  34     ISSN:  0021-5155     ISO Abbreviation:  Jpn. J. Ophthalmol.     Publication Date:  1990  
Date Detail:
Created Date:  1990-11-01     Completed Date:  1990-11-01     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0044652     Medline TA:  Jpn J Ophthalmol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  133-41     Citation Subset:  IM    
Institute of Ophthalmology, Tane Memorial Eye Hospital, Osaka, Japan.
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MeSH Terms
Blood-Retinal Barrier / drug effects,  physiology*
Body Water / metabolism

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