Document Detail


Fluid and electrolyte supplementation after prolonged moderate-intensity exercise enhances muscle glycogen resynthesis in Standardbred horses.
MedLine Citation:
PMID:  18948447     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We hypothesized that postexercise rehydration using a hypotonic electrolyte solution will increase the rate of recovery of whole body hydration, and that this is associated with increased muscle glycogen and electrolyte recovery in horses. Gluteus medius biopsies and jugular venous blood were sampled from six exercise-conditioned Standardbreds on two separate occasions, at rest and for 24 h following a competitive exercise test (CET) designed to simulate the speed and endurance test of a 3-day event. After the CETs, horses were given water ad libitum, and either a hypotonic commercial electrolyte solution (electrolyte) via nasogastric tube, followed by a typical hay/grain meal, or a hay/grain meal alone (control). The CET resulted in decreased total body water and muscle glycogen concentration of 8.4 +/- 0.3 liters and 22.6%, respectively, in the control treatment, and 8.2 +/- 0.4 liters and 21.9% in the electrolyte treatment. Electrolyte resulted in an enhanced rate of muscle glycogen resynthesis and faster restoration of hydration (as evidenced by faster recovery of plasma protein concentration, maintenance of plasma osmolality, and greater muscle intracellular fluid volume) during the recovery period compared with control. There were no differences in muscle Na, K, Cl, or Mg contents between the two treatments. It is concluded that oral administration of a hypotonic electrolyte solution after prolonged moderate-intensity exercise enhanced the rate of muscle glycogen resynthesis during the recovery period compared with control. It is speculated that postexercise dehydration may be one key contributor to the slow muscle glycogen replenishment in horses.
Authors:
Amanda P Waller; George J F Heigenhauser; Raymond J Geor; Lawrence L Spriet; Michael I Lindinger
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-10-23
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  106     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-09     Completed Date:  2009-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  91-100     Citation Subset:  IM    
Affiliation:
Dept. of Human Health and Nutritional Sciences, Univ. of Guelph, Guelph, ON, Canada N1G 2W1. awaller@uoguelph.ca
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Animal Feed
Animal Nutritional Physiological Phenomena
Animals
Blood Glucose / metabolism
Blood Proteins / metabolism
Body Water / metabolism
Chlorides / blood
Fluid Therapy / veterinary*
Glycogen / metabolism*
Horses
Hypotonic Solutions / administration & dosage*
Magnesium / blood
Male
Muscle Contraction*
Muscle, Skeletal / metabolism*
Osmolar Concentration
Physical Conditioning, Animal*
Potassium / blood
Sodium / blood
Time Factors
Water-Electrolyte Balance*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Blood Proteins; 0/Chlorides; 0/Hypotonic Solutions; 7439-95-4/Magnesium; 7440-09-7/Potassium; 7440-23-5/Sodium; 9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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