| Fludeoxyglucose positron emission tomography in the diagnosis of giant cell arteritis. | |
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MedLine Citation:
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PMID: 11295964 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a case in which fludeoxyglucose F 18 positron emission tomography (PET) led directly to the diagnosis of giant cell arteritis in an elderly woman with a fever of unknown origin. The patient presented with a 3-month history of fatigue, fever, headache, visual disturbance, jaw claudication, and anemia. A computed tomographic scan showed an anterior mediastinal mass that was suspected of being malignant. A fludeoxyglucose F 18 PET scan performed for preoperative evaluation identified striking uptake of fludeoxyglucose F 18 in the walls of the entire aorta, left main coronary artery, and subclavian, carotid, and common iliac arteries bilaterally, suggestive of an arteritis, a diagnosis subsequently confirmed by the findings of an arterial biopsy. Her erythrocyte sedimentation rate was 129 mm/h. There was normalizaton of the PET scan 2 weeks following treatment with prednisolone. This case suggests that fludeoxyglucose F 18 PET contributes to the noninvasive diagnosis of giant cell arteritis, as well as to the evaluation of the extent of disease, response to therapy, and disease recurrence. |
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Authors:
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A Turlakow; H W Yeung; J Pui; H Macapinlac; E Liebovitz; V Rusch; A Goy; S M Larson |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of internal medicine Volume: 161 ISSN: 0003-9926 ISO Abbreviation: Arch. Intern. Med. Publication Date: 2001 Apr |
Date Detail:
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Created Date: 2001-04-11 Completed Date: 2001-05-03 Revised Date: 2009-11-03 |
Medline Journal Info:
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Nlm Unique ID: 0372440 Medline TA: Arch Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 1003-7 Citation Subset: AIM; IM |
Affiliation:
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Nuclear Medicine Service, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA. aturlakow@ozemail.com.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anemia, Hypochromic / etiology Anti-Inflammatory Agents / therapeutic use Biopsy Blood Sedimentation Fatigue / etiology Female Fever of Unknown Origin / etiology Fluorodeoxyglucose F18 / diagnostic use* Giant Cell Arteritis / blood, complications, drug therapy, radionuclide imaging* Headache / etiology Humans Prednisolone / therapeutic use Radiopharmaceuticals / diagnostic use* Tomography, Emission-Computed / methods* Tomography, X-Ray Computed Weight Loss |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Radiopharmaceuticals; 50-24-8/Prednisolone; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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