Document Detail


Fluctuations in alveolar CO2 and in base excess during the menstrual cycle.
MedLine Citation:
PMID:  935695     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
End-tidal PCO2 and base excess were measured on 10 healthy females throughout a total of 16 menstrual cycles. A corresponding decrease was observed in both variables during the luteal phase of the cycle. The curve for PCO2 was essentially that reported by previous authors, the tension dropping from a mean value of 39.8 to 36.7, 10 days after ovulation. The parallel drop in BE lowered the variable from -0.5 to -2.6. The resulting arterial pH throughout the cycle was calculated to be between 7.38 and 7.40. Since no time lag could be observed between the change in PCO2 and that of base excess, the primary disturbance could be either a ventilatory or metabolic response to an increase in progesterone during the luteal phase. In either case, a considerable decrease in body CO2 stores must result from these changes.
Authors:
S J England; L E Farhi
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Respiration physiology     Volume:  26     ISSN:  0034-5687     ISO Abbreviation:  Respir Physiol     Publication Date:  1976 Apr 
Date Detail:
Created Date:  1976-09-01     Completed Date:  1976-09-01     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0047142     Medline TA:  Respir Physiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  157-61     Citation Subset:  IM; S    
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MeSH Terms
Descriptor/Qualifier:
Acid-Base Equilibrium* / drug effects
Adult
Alkalosis, Respiratory / metabolism
Carbon Dioxide / metabolism*
Female
Humans
Luteal Phase*
Menstruation*
Partial Pressure
Progesterone / pharmacology
Pulmonary Alveoli / metabolism*
Respiration / drug effects
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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