| Fluctuations of arterial blood pressure decrease with mechanical ventilation in premature infants with respiratory distress syndrome. | |
| | |
MedLine Citation:
|
PMID: 2213267 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Marked fluctuations of arterial blood pressure (ABP) are associated with an increased risk of intraventricular hemorrhage. The pathophysiology is linked to spontaneous breathing. We hypothesized that these fluctuations would decrease after initiation of effective mechanical ventilation. We studied 20 infants treated with nasal continuous positive airway pressure (CPAP) and oxygen for early respiratory distress. Eleven required intubation for clinical indications. Simultaneous ABP and respiratory tracing obtained before and following intubation were analyzed for average peak systolic blood pressure (SBP) and the percentage of spontaneous respirations (SResp). Fluctuations of SBP were quantitated using the coefficient of variation (CV). The remaining 9 infants with minimal lung disease served as a control group. There was a small increase in SBP, and a marked decrease in both CV and SResp following intubation. A significant correlation was found between the percent decreases in CV and SResp. We conclude that beat-to-beat fluctuations of ABP decrease after the initiation of effective mechanical ventilation. This effect is primarily due to a decrease in spontaneous breathing. |
| | |
Authors:
|
R F Goldstein; J E Brazy |
Related Documents
:
|
9631807 - Delivery of inhaled nitric oxide using the ohmeda inovent delivery system. 10809307 - Chylothorax: a novel therapy. 11353547 - Comparison of high-frequency flow interruption ventilation and hyperventilation in pers... 2582847 - Analysis of resistance to gas flow in nine adult ventilator circuits. 2902117 - Activation of gastric afferent fibers increases coronary arterial resistance in anesthe... 3600177 - Reduced coronary vasoconstrictor activity of hemoglobin solutions purified by atp-agaro... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 10 ISSN: 0743-8346 ISO Abbreviation: J Perinatol Publication Date: 1990 Sep |
Date Detail:
|
Created Date: 1990-10-31 Completed Date: 1990-10-31 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 267-71 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, Duke University Medical Center, Durham, NC 27710. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Pressure
/
physiology* Humans Infant, Newborn Infant, Premature* Intubation, Intratracheal Monitoring, Physiologic Myocardial Contraction Positive-Pressure Respiration Prospective Studies Regression Analysis Respiration / physiology Respiration, Artificial* Respiratory Distress Syndrome, Newborn / physiopathology*, therapy |
| Grant Support | |
ID/Acronym/Agency:
|
HDO6957-01/HD/NICHD NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Perinatal outcome of singleton pregnancies conceived by in vitro fertilization: a controlled study.
Next Document: Fatal Streptococcus viridans septicemia and meningitis: relationship to fetal scalp electrode monito...