Document Detail

Fluconazole therapy for Candida albicans urinary tract infections in infants.
MedLine Citation:
PMID:  12172774     Owner:  NLM     Status:  MEDLINE    
Candiduria is rare in newborns and infants, occurring most often in patients with risk factors. When associated with a candidal bezoar in the urinary tract, candiduria is usually treated by systemic amphotericin B and flucytosine plus local irrigation with amphotericin B. We describe the successful treatment of five newborns with a urinary tract infection, on major urological malformations, due to Candida albicans (including three with a candidal bezoar) by fluconazole alone. No adverse effects or recurrences were observed. Fluconazole therapy permits early discharge from the hospital and seems suitable for infants and newborns with a C. albicans urinary tract infection.
Valérie Triolo; Martine Gari-Toussaint; Florence Casagrande; Rodolphe Garraffo; Christian Dageville; Patrick Boutté; Etienne Bérard
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2002-06-21
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  17     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-08-12     Completed Date:  2003-02-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  550-3     Citation Subset:  IM    
Département de Pédiatrie, Hôpital de l'Archet 2, 151 avenue de Saint Antoine de Ginestière, BP 3079, 06202 Nice Cedex, France.
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MeSH Terms
Antifungal Agents / blood,  therapeutic use*
Bezoars / drug therapy
Candidiasis / drug therapy*
Fluconazole / blood,  therapeutic use*
Follow-Up Studies
Infant, Newborn
Treatment Outcome
Urinary Tract Infections / drug therapy*
Reg. No./Substance:
0/Antifungal Agents; 86386-73-4/Fluconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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