Document Detail

Flubiprofen vs dipyrone combined with hyoscine: the analgesic efficacy in renal colic
MedLine Citation:
PMID:  8554391     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: We compared the efficacy of flurbiprofen (NSAID) versus dipirone + hyoscine N-butylbromide in the treatment of nephric colic. METHODS: The study comprised 135 patients, aged 18 to 75 yrs, with intense nephric colic. The patients were observed 60 min after a single IM dose of 150 mg flurbiprofen (n = 67) or 2 gm dipirone + 20 mg hyoscine N-butylbromide. RESULTS: Both treatment modalities were well-tolerated and afforded significant pain relief. Flurbiprofen, however, was faster-acting and superior to dipirone + hyoscine in the overall evaluation of good and excellent therapeutic response rates. CONCLUSION: The results of the study show that IM flurbiprofen is a useful alternative to dipirone + hyoscine N-butylbromide in the treatment of nephric colic.
M J Mora Durban; J Extramiana Cameno; M Arrizabalaga Moreno; P Paniagua Andrés; J Camp Herrero; J Milla Santos; F del Nogal Saez; F Gimeno Albo; E Moreno Carretero; R Domínguez Granados
Publication Detail:
Type:  Clinical Trial; Clinical Trial, Phase III; Comparative Study; English Abstract; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Archivos españoles de urología     Volume:  48     ISSN:  0004-0614     ISO Abbreviation:  Arch. Esp. Urol.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-02-20     Completed Date:  1996-02-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0064757     Medline TA:  Arch Esp Urol     Country:  SPAIN    
Other Details:
Languages:  spa     Pagination:  867-73     Citation Subset:  IM    
Servicio de Urología, Hospital de Móstoles, Madrid, España.
Vernacular Title:
Flubiprofeno vs dipirona asociada a hioscina: eficacia analgésica en el cólico nefrítico.
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MeSH Terms
Analysis of Variance
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Butylscopolammonium Bromide / therapeutic use*
Chi-Square Distribution
Colic / drug therapy*
Dipyrone / therapeutic use*
Double-Blind Method
Drug Therapy, Combination
Flurbiprofen / therapeutic use*
Kidney Diseases / drug therapy*
Middle Aged
Scopolamine / therapeutic use*
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 149-64-4/Butylscopolammonium Bromide; 51-34-3/Scopolamine; 5104-49-4/Flurbiprofen; 68-89-3/Dipyrone

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