Document Detail


Flu-like symptoms associated with fluoxetine overdose: a case report.
MedLine Citation:
PMID:  2628588     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The serotonin reuptake inhibitor zimelidine may cause flu-like symptoms and Guillain-Barre syndrome. Guillain-Barre syndrome has not been reported with the use of the structurally related serotonin reuptake inhibitor fluoxetine. Flu-like symptoms are described in the manufacturer's literature on fluoxetine but are absent from published studies. We describe a patient who developed flu-like symptoms, urticaria and angioedema 2 days after fluoxetine overdose. There were no neurologic sequelae. This case confirms that fluoxetine may be associated with flu-like symptoms and suggests that, because these symptoms occurred after overdose, they may be dose related. The additional findings in this patient suggestive of allergy, an unusual feature of drug overdose, are discussed.
Authors:
S W Kim; P R Pentel
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of toxicology. Clinical toxicology     Volume:  27     ISSN:  0731-3810     ISO Abbreviation:  J. Toxicol. Clin. Toxicol.     Publication Date:  1989  
Date Detail:
Created Date:  1990-04-19     Completed Date:  1990-04-19     Revised Date:  2005-11-22    
Medline Journal Info:
Nlm Unique ID:  8213460     Medline TA:  J Toxicol Clin Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  389-93     Citation Subset:  AIM; IM    
Affiliation:
Department of Psychiatry, Hennepin County Medical Center, University of Minnesota, Minneapolis 55455.
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MeSH Terms
Descriptor/Qualifier:
Adult
Emergencies
Female
Fluoxetine / poisoning*
Humans
Hypersensitivity, Delayed / physiopathology*
Influenza, Human / physiopathology*
Suicide, Attempted
Chemical
Reg. No./Substance:
54910-89-3/Fluoxetine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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