Document Detail

Flows of dioxins and furans in coastal food webs: inverse modeling, sensitivity analysis, and applications of linear system theory.
MedLine Citation:
PMID:  16494250     Owner:  NLM     Status:  MEDLINE    
Rate constant bioaccumulation models are applied to simulate the flow of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in the coastal marine food web of Frierfjorden, a contaminated fjord in southern Norway. We apply two different ways to parameterize the rate constants in the model, global sensitivity analysis of the models using Extended Fourier Amplitude Sensitivity Test (Extended FAST) method, as well as results from general linear system theory, in order to obtain a more thorough insight to the system's behavior and to the flow pathways of the PCDD/Fs. We calibrate our models against observed body concentrations of PCDD/Fs in the food web of Frierfjorden. Differences between the predictions from the two models (using the same forcing and parameter values) are of the same magnitude as their individual deviations from observations, and the models can be said to perform about equally well in our case. Sensitivity analysis indicates that the success or failure of the models in predicting the PCDD/F concentrations in the food web organisms highly depends on the adequate estimation of the truly dissolved concentrations in water and sediment pore water. We discuss the pros and cons of such models in understanding and estimating the present and future concentrations and bioaccumulation of persistent organic pollutants in aquatic food webs.
Tuomo M Saloranta; Tom Andersen; Kristoffer Naes
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental toxicology and chemistry / SETAC     Volume:  25     ISSN:  0730-7268     ISO Abbreviation:  Environ. Toxicol. Chem.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-02-23     Completed Date:  2006-06-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8308958     Medline TA:  Environ Toxicol Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  253-64     Citation Subset:  IM    
Norwegian Institute for Water Research, P.O. Box 173 Kjelsăs, N-0411 Oslo, Norway.
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MeSH Terms
Benzofurans / metabolism*
Computer Simulation
Food Chain*
Models, Biological*
Reproducibility of Results
Sensitivity and Specificity
Tetrachlorodibenzodioxin / analogs & derivatives*,  metabolism
Water Pollutants, Chemical / metabolism*
Reg. No./Substance:
0/Benzofurans; 0/Water Pollutants, Chemical; 0/chlorinated dibenzofurans; 0/polychlorodibenzo-4-dioxin; 1746-01-6/Tetrachlorodibenzodioxin

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