Document Detail

Flow volume in the common carotid artery detected by color duplex sonography: an approach to the normal value and predictability of cerebral blood flow.
MedLine Citation:
PMID:  11246999     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine normal common carotid artery (CCA) flow volume, its relationship with age, and the predictability of cerebral blood flow (CBF) by color duplex sonography. SUBJECTS AND METHODS: Forty-five healthy subjects (18 men, 27 women, 23-86 years old) and 13 patients (3 men, 10 women, 51-88 years old) without neurological disease underwent color duplex sonography. All 13 patients also underwent xenon CT. CCA flow volume in the healthy subjects was measured to determine normal values. This volume was divided by mean brain weight to estimate CBF, which was correlated with CBF measured by xenon CT in regions of ipsilateral internal carotid arteries (ICA). RESULTS: In healthy subjects, CCA flow volume ranged from 155.0-458.8 ml/min (mean+/-SD: 267.77+/-59.91), corresponding to an estimated CBF of 12.43-32.84 ml/min/100 g brain weight (mean+/-SD: 20.63+/-4.22). No relationship was found between flow volume and age. A good correlation was found between estimated CBF and CBF measured by xenon CT in regions of both ICAs (gamma=0.713, p=0.0062 on the left; gamma=0.686, p=0.0096 on the right). CONCLUSION: By using color duplex sonography, we established a set of normal CCA flow volumes, which do not decline with age. Estimated CBF derived from flow volume can predict actual CBF.
B C Chu; A Narita; K Aoki; T Yoshida; T Warabi; K Miyasaka
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Radiation medicine     Volume:  18     ISSN:  0288-2043     ISO Abbreviation:  Radiat Med     Publication Date:    2000 Jul-Aug
Date Detail:
Created Date:  2001-03-14     Completed Date:  2001-06-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8412264     Medline TA:  Radiat Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  239-44     Citation Subset:  IM    
Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan.
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MeSH Terms
Aged, 80 and over
Aging / physiology
Blood Flow Velocity
Carotid Artery, Common / ultrasonography*
Cerebrovascular Circulation*
Middle Aged
Reference Values
Ultrasonography, Doppler, Color
Ultrasonography, Doppler, Transcranial
Xenon / diagnostic use
Reg. No./Substance:

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